effect of alcohol on drug bioavailability [Study Performance]
Dear Helmut (and I'm sure ElMaestro will be interested in this somewhat off-topic discussion),
I think there is a need for further studies on the influence of various factors such as the way you drink your whisky: dry, or with ice, or with carbonated water, or both. This could influence gastric emptying. Also what you eat along could introduce some variability (how much, and how fat it is).
Once again dissolution testing will never replace human studies.
Regards
Ohlbe
❝ alcohol is one the few drugs which are very rapidly absorbed from the stomach - so nothing will be left before the absorption from the formulation will have a chance to start.
I think there is a need for further studies on the influence of various factors such as the way you drink your whisky: dry, or with ice, or with carbonated water, or both. This could influence gastric emptying. Also what you eat along could introduce some variability (how much, and how fat it is).
Once again dissolution testing will never replace human studies.
Regards
Ohlbe
—
Regards
Ohlbe
Regards
Ohlbe
Complete thread:
- effect of alcohol on drug bioavailability Dr.Niraj Limbachiya 2010-02-06 09:15
- effect of alcohol on drug bioavailability Helmut 2010-02-06 13:32
- effect of alcohol on drug bioavailability Ohlbe 2010-02-07 23:54
- effect of alcohol on drug bioavailability Helmut 2010-02-07 23:58
- effect of alcohol on drug bioavailability Ohlbe 2010-02-08 00:36
- effect of alcohol on drug bioavailability Helmut 2010-02-08 14:08
- effect of alcohol on drug bioavailability Ohlbe 2010-02-08 17:01
- effect of alcohol on drug bioavailability Helmut 2010-02-08 17:07
- effect of alcohol on drug bioavailability ElMaestro 2010-02-08 18:19
- effect of alcohol on drug bioavailability mvgchakravarthi 2010-02-15 17:41
- exact definitions ElMaestro 2010-02-15 18:31
- exact definitions mvgchakravarthi 2010-02-16 15:32
- exact definitions Ohlbe 2010-02-16 17:11
- exact definitions mvgchakravarthi 2010-02-16 15:32
- exact definitions ElMaestro 2010-02-15 18:31
- effect of alcohol on drug bioavailability mvgchakravarthi 2010-02-15 17:41
- effect of alcohol on drug bioavailability Ohlbe 2010-08-05 00:27
- effect of alcohol on drug bioavailability ElMaestro 2010-02-08 18:19
- effect of alcohol on drug bioavailability Helmut 2010-02-08 17:07
- effect of alcohol on drug bioavailability Ohlbe 2010-02-08 17:01
- effect of alcohol on drug bioavailability Helmut 2010-02-08 14:08
- effect of alcohol on drug bioavailability Ohlbe 2010-02-08 00:36
- effect of alcohol on drug bioavailability Helmut 2010-02-07 23:58
- effect of alcohol on drug bioavailabilityOhlbe 2010-02-16 17:17
- effect of alcohol on drug bioavailability ElMaestro 2010-02-16 21:11
- effect of alcohol on drug bioavailability Ohlbe 2010-02-07 23:54
- effect of alcohol on drug bioavailability Helmut 2010-02-06 13:32