Bioequivalence and Bioavailability Forum

exact definitions [Study Performance]

posted by Ohlbe – France, 2010-02-16 18:11 (5977 d 06:45 ago) – Posting: # 4774
Views: 14,939

Dear M.V.g.chakravarthi

❝ my question is when i compared dissolution of BCS class I molecule in 40% alcohol with Reference sample i got 8% for test and whereas 3% for Reference at 2hrs. is it indicates test sample is dose dumping?

No. If you only have 8 % dissolution after 2 h, considering the time during which the drug will be in contact with alcohol in the stomach, no problem.

Regards
Ohlbe

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Regards
Ohlbe

Complete thread:

effect of alcohol on drug bioavailability Dr.Niraj Limbachiya 2010-02-06 09:15
- effect of alcohol on drug bioavailability Helmut 2010-02-06 13:32
  - effect of alcohol on drug bioavailability Ohlbe 2010-02-07 23:54
    - effect of alcohol on drug bioavailability Helmut 2010-02-07 23:58
      - effect of alcohol on drug bioavailability Ohlbe 2010-02-08 00:36
        
        effect of alcohol on drug bioavailability Helmut 2010-02-08 14:08
        
        effect of alcohol on drug bioavailability Ohlbe 2010-02-08 17:01
        
        effect of alcohol on drug bioavailability Helmut 2010-02-08 17:07
        
        effect of alcohol on drug bioavailability ElMaestro 2010-02-08 18:19
        
        effect of alcohol on drug bioavailability mvgchakravarthi 2010-02-15 17:41
        
        exact definitions ElMaestro 2010-02-15 18:31
        
        exact definitions mvgchakravarthi 2010-02-16 15:32
        
        exact definitionsOhlbe 2010-02-16 17:11
        
        effect of alcohol on drug bioavailability Ohlbe 2010-08-05 00:27
        
        Cheers! Helmut 2010-08-05 00:45
        
        Cheers! Ohlbe 2010-08-06 22:21
  - effect of alcohol on drug bioavailability Ohlbe 2010-02-16 17:17
    - effect of alcohol on drug bioavailability ElMaestro 2010-02-16 21:11

exact definitions [Study Per­for­mance]

Complete thread:

exact definitions [Study Performance]