Bioequivalence and Bioavailability Forum

exact definitions [Study Performance]

posted by ElMaestro – Denmark, 2010-02-15 19:31 (5975 d 22:24 ago) – Posting: # 4766
Views: 14,848

Dear M.V.G.Chakravarthi

❝ 1. definition of Dose dumping?

❝ 2. Is there any limits permitted for this?

❝ 3. when we compared with innovator is it compulsory to match dissolution in 40% v/v alcohol?

I am no expert, but here are my guesses:

D.D. is in this context free fantasy.
Inside the minds of affected people it is manifestating itself through the mental picture of a controlled release tablet or capsule releasing the active ingredient(s) all at once, thereby being a serious risk to public health. As the nature of D.D. is fantasy we can think of it in much the same fashion as we imagine San Marino winning the world cup in football or getting hit by a falling coconut on the South Pole.
I'm not ware of any. However, we should bear in mind that delusions are not too uncommon in the general population. Is there a psychiatrist present?
If I were you I'd test the dissolution in the ordinary fashion and use the alcohol for a great party.

Best regards
EM.