effect of alcohol on drug bioavailability [Study Per­for­mance]

posted by Helmut Homepage – Vienna, Austria, 2010-02-08 15:08 (5985 d 06:47 ago) – Posting: # 4732
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Dear Ohlbe!

Well, I knew that one – I would file it in the myth-section. ;-)
The company showed no influence on the release in vitro (which in that case is more rigourous than any in vivo study: dissolution in 40% alcohol), but had to place a warning in the SPC…
Recently I had to deal with the DCP of a paediatric (!), where similar concerns were expressed.
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