effect of alcohol on drug bioavailability [Study Per­for­mance]

posted by Ohlbe – France, 2010-02-08 00:54 (5573 d 03:13 ago) – Posting: # 4728
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Dear Helmut,

❝ A better release of the API from the formulation (enhanced solubility) I would consider a myth, because alcohol is one the few drugs which are very rapidly absorbed from the stomach – so nothing will be left before the absorption from the formulation will have a chance to start.


Well... There are discussions about some modified release formulations, where the coating could be damaged by alcohol, resulting in dose dumping. Avoid taking your ER morphine with a large glass of whisky.

Regards
Ohlbe

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