median Tmax [Study Per­for­mance]

posted by mittyri  – Russia, 2019-10-17 02:01 (2439 d 17:11 ago) – Posting: # 20698
Views: 8,349

Hi Helmut,

❝ For the IR formulation most people opt at two times the median tmax.


that's right, but in such case the PK scientist should know the median before the analysis starts, should he? Or to exclude the subject after PK analysis, when the median is calculated? Or should he use the published median Tmax?

Kind regards,
Mittyri

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,571 registered users;
142 visitors (0 registered, 142 guests [including 32 identified bots]).
Forum time: 19:13 CEST (Europe/Vienna)

Science is simply common sense at its best that is,
rigidly accurate in observation, and
merciless to fallacy in logic.    Thomas Henry Huxley

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5