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RegisterUniform dosing time is required to be followed for study [Study Performance]
Hi vivekanand,
it shouldn't be too much of a deal, but at least in theory it might affect your result; the dosing slot in period 2 will, if I get you right, be a between subject issue and from that perspective it will not be affecting the intra-subject variability. But if you the phlebotomist or someone/something in slot 2 is causing the variability to differ from slot 1 then it will impact the apparent within-subject variability and thus your CI.
I think it is up to you to judge any impact. Only people who are intimately familiar with how things work in your clinic can judge it, I think. it is fairly common for logistical reasons to dose some people at 7am, others at 8am etc.
it shouldn't be too much of a deal, but at least in theory it might affect your result; the dosing slot in period 2 will, if I get you right, be a between subject issue and from that perspective it will not be affecting the intra-subject variability. But if you the phlebotomist or someone/something in slot 2 is causing the variability to differ from slot 1 then it will impact the apparent within-subject variability and thus your CI.
I think it is up to you to judge any impact. Only people who are intimately familiar with how things work in your clinic can judge it, I think. it is fairly common for logistical reasons to dose some people at 7am, others at 8am etc.
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Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Uniform dosing time is required to be followed for study vivekanand 2015-01-19 05:54
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Uniform dosing time is required to be followed for studyElMaestro 2015-01-19 11:41
Ing. Helmut Schütz