blood loss < donation (500ml) [Study Performance]
Dear Vishal,
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No guideline I know of.
Generally blood loss comparable to a single bood donation (500 mL) in a 2-period study does not rise medical/ethical concerns. IMHO your planned design should not be problematic.
since you have agreed with the forum's policy during registration, you do remember following lines for sure:
It's nice to start your post with a salutation, and include a signature as well.
You may save a signature with your User's data; it will be automatically attached to your posts.
❝ … total blood loss is 480ml in 4 Periods with wash out period of one week between periods.
❝ Do you know of any guideline which says that we need to check the Hb (hemoglobin) of the subjects before the start of Period III.
No guideline I know of.
Generally blood loss comparable to a single bood donation (500 mL) in a 2-period study does not rise medical/ethical concerns. IMHO your planned design should not be problematic.
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- total blood loss vish14184 2007-11-15 11:05
- blood loss < donation (500ml)Helmut 2007-11-15 15:53
- blood loss < donation (500ml) M.Vasu 2007-11-17 04:31
- blood loss < donation (500ml) Jaime_R 2007-11-17 14:10
