Bioequivalence and Bioavailability Forum

additional water to subject [Study Performance]

posted by Helmut – Vienna, Austria, 2013-06-25 17:56 (4338 d 17:32 ago) – Posting: # 10877
Views: 5,518

Dear Dan & Suchit

❝ […] I see no reason why the subject should be so thirsty that he should drink an additional amount of any kind of beverage within 2 hours after administration.

Since Suchit wrote

❝ […] subject requesting for additional water to consume investigational product

I guess this was not a question of being thirsty. If the drug sticks to the esophagus it might play havoc to absorption. In such a case I would allow for some more water to make sure the drug reaches the stomach.

❝ If he does it is a protocol deviation which has to be recorded.

Agree.

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Complete thread:

additional water to subject suchit_bhavsar 2013-06-25 11:06
- additional water to subject Dr_Dan 2013-06-25 14:38
  - additional water to subjectHelmut 2013-06-25 15:56
    - additional water to subject Dr_Dan 2013-06-25 16:24
    - additional water to subject suchit_bhavsar 2013-06-26 05:20
      - additional water to subject raghu 2013-06-28 08:24
        
        Science driven decisions Helmut 2013-06-28 14:22

additional water to subject [Study Per­for­mance]

Complete thread:

additional water to subject [Study Performance]