Bioequivalence and Bioavailability Forum

Bioavailability Calculation [Software]

posted by SriRam  – India, 2012-04-08 09:49 (4763 d 09:21 ago) – Posting: # 8395
Views: 8,823

Hello,
I have a question regarding calculation of bioavailability using WinNonlin.

1. How does WinNonlin report bioavailability? (Parameters considered)
   
2. A more basic question is the Bioavailability equation
   (F = DNAUC po / DNAUC iv) Valid for Both Linear Pharmacokinetics (Linear and stationary) and Nonlinear Pharmacokinetics
   Ref: http://www.ncbi.nlm.nih.gov/pubmed/15601440

Waiting for all valuble suggestions and discussion relating to Discovery PK of NCE.

Complete thread:

• Bioavailability CalculationSriRam 2012-04-08 07:49 
  • Bioavailability Calculation (WinNonlin) Helmut 2012-04-08 12:41
    • Bioavailability Calculation (WinNonlin) SriRam 2012-04-08 15:02
      • Area-correction method Helmut 2012-04-09 02:20
        • Area-correction method SriRam 2012-04-09 15:40