Bioequivalence and Bioavailability Forum • SAS and missing values

SAS and missing values [Software]

posted by Shuanghe – Spain, 2012-01-13 12:17 (5274 d 03:24 ago) – Posting: # 7924
Views: 9,445

Hi Helmut, Happy new year.

I also tested FDA's SABE approach using SAS 9.2 on EMA's datasets. Firstly, for your question. SAS does treat missing data as period symbol '.' by default.

With regards to the result, I have identical result (well, less decimals than yours :-D

) for 3 periods dataset, but for full replicate data, I have same x, boundx and pointest values as yours but different values for other parameters. e.g.

S2wr      =  0.19931

Swr       =  0.44645

y         = -0.15879

boundy    = -0.12299

critbound = -0.092076

Those values were calculated based on Dlat and we should have 73 Dlat values. If I understood your post, you have 69? But 69 is the number of Ilat. Don't know if this is the reason we have different result.

Can anyone firstly check it using SAS, then using Phoenix or R?

Thanks.

—
All the best,
Shuanghe

Complete thread:

SAS and missing values Helmut 2012-01-06 01:47
- SAS and missing valuesShuanghe 2012-01-13 11:17
  - THX & another request Helmut 2012-01-13 13:31
    - Congratulations for both of us :-D Shuanghe 2012-01-13 16:14
      - FDA's RSABE: Phoenix ‘validated’ against SAS Helmut 2012-01-13 16:39
        
        How to obtain CINV value in Phoenix Shuanghe 2012-01-19 11:43
        
        Import from external source Helmut 2012-01-19 14:24
        
        Thanks, it's done!! Shuanghe 2012-01-19 22:42
        
        Thanks, it's done!! Helmut 2012-01-20 00:10
- SAS and missing values JMCardot 2012-01-31 03:12