Bioequivalence and Bioavailability Forum

Power of superiority [Software]

posted by Helmut  – Vienna, Austria, 2011-11-10 15:39 (4912 d 20:35 ago) – Posting: # 7650
Views: 10,069

Dear Detlew,

was really nice meeting you yesterday!
BTW, fog at both Berlin’s and Vienna’s airports; arrived at home at midnight…

❝ I can't reproduce the numbers because I don't have RefLSM and the DiffSE. Yicaoting, be so kind to post them here.

Results form PHX/WNL’s BE output (standard model; subject(sequence) random):

Full dataset (balanced; n_RT=n_TR=12)
Untransformed
LSMRef   82.559375          SERef  4.34005723555842
LSMTest  80.271875          SETest 4.34005723555842
LSMDiff  -2.28750000000002  SEDiff 3.73326038107666
‘Power’   0.9935408
ln transformed
LSMRef   4.37972882180257   SERef  0.05625992661764
LSMTest  4.35107672956901   SETest 0.05625992661764
LSMDiff -0.028652092233559  SEDiff 0.055693090418743 (corrected; see here – was 0.02865…)
‘Power’  0.9839865

Reduced dataset (imbalanced; 23/24 excluded: n_RT=10, n_TR=12)
Untransformed
LSMRef   83.9116666666666   SERef  4.59672942436518
LSMTest  81.5147916666666   SETest 4.59672942436518
LSMDiff  -2.39687499999999  SEDiff 3.81747472994938
‘Power’   0.99266427
ln transformed
LSMRef   4.39812486326424   SERef  0.059448124239987
LSMTest  4.35107672956901   SETest 0.059448124239987
LSMDiff -0.032751848318541  SEDiff 0.057311390736542
‘Power’  0.97882724

❝ I would state: Approximate correct for the problem stated but answers a question no one has asked .

Great.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• The secret of WinNonlin's BE's post-hoc Power analysis yicaoting 2011-11-08 14:40 
  • The secret of WinNonlin's BE's post-hoc Power analysis yicaoting 2011-11-08 14:55
  • The secret of WinNonlin's BE's post-hoc Power analysis Helmut 2011-11-08 15:06
  • Power of superiority d_labes 2011-11-10 09:49
    • Power of superiorityHelmut 2011-11-10 14:39
      • Power of equality d_labes 2011-11-10 16:42
        • Power of equality Helmut 2011-11-10 17:00
          • Power of equality test - 2nd try for the logs d_labes 2011-11-11 09:55
            • Crtl-C/Ctrl-V Helmut 2011-11-11 14:39
        • Power of equality yicaoting 2011-11-12 07:05