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RegisterWinNonlin’s BE wizard is known to be buggy [Software]
posted by Helmut 
– Vienna, Austria, 2011-11-06 17:53 (5344 d 00:57 ago) – Posting: # 7627
Views: 13,546
Dear yicaoting!
Consider upgrading to Phoenix. It’s free of charge and support for ‘classical’ WinNonlin will end soon. In PHX I have set up a workflow running both the BE wiz and LME. Results are compared and if the difference in both CLs is ≤0.01 % (the magic rounding requirement according to FDA and EMA: 80.00 % ≤ CI ≤ 125.00 %) I use BE’s results. Although fancy stuff is included in WNL (M$-Word export) and PHX (+HTML tables) I never use them. Takes ages to set them up – much easier to import the ASCII-text into a statistical report.
If you really bother (and after this this post I’m sure you don’t) and have a lot of money to spare you can obtain a Phoenix Connect-license. Then it would be possible to get the t-value from an R-script.
There’s another point on my wishlist: Have you ever tried to reproduce WNL’s reported power in any other piece of software?
❝ I will be careful with WNL's BE wizard.
Consider upgrading to Phoenix. It’s free of charge and support for ‘classical’ WinNonlin will end soon. In PHX I have set up a workflow running both the BE wiz and LME. Results are compared and if the difference in both CLs is ≤0.01 % (the magic rounding requirement according to FDA and EMA: 80.00 % ≤ CI ≤ 125.00 %) I use BE’s results. Although fancy stuff is included in WNL (M$-Word export) and PHX (+HTML tables) I never use them. Takes ages to set them up – much easier to import the ASCII-text into a statistical report.
❝ Your suggestion is definitely valuable if one wants to get high-precision results (at least for 90% CI of the ratio).
If you really bother (and after this this post I’m sure you don’t) and have a lot of money to spare you can obtain a Phoenix Connect-license. Then it would be possible to get the t-value from an R-script.
There’s another point on my wishlist: Have you ever tried to reproduce WNL’s reported power in any other piece of software?
—
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Helmut Schütz
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The quality of responses received is directly proportional to the quality of the question asked. 🚮
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- WinNonlin is lack of precision or? yicaoting 2011-11-06 13:03
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- WinNonlin is lack of precision or? ElMaestro 2011-11-06 13:46
- WinNonlin is lack of precision or? yicaoting 2011-11-06 14:20
- WinNonlin is lack of precision or? ElMaestro 2011-11-06 14:32
- WinNonlin is lack of precision or? yicaoting 2011-11-06 14:59
- EOD? Helmut 2011-11-06 15:39
- WinNonlin is lack of precision or? yicaoting 2011-11-06 14:59
- WinNonlin is lack of precision or? Helmut 2011-11-06 14:46
- use an ox cleaver to kill a chicken yicaoting 2011-11-06 15:25
- use an ox cleaver to kill a chicken Helmut 2011-11-06 15:47
- use an ox cleaver to kill a chicken yicaoting 2011-11-06 15:25
- WinNonlin is lack of precision or? ElMaestro 2011-11-06 14:32
- WinNonlin is lack of precision or? yicaoting 2011-11-06 14:20
- WinNonlin’s BE wizard is known to be buggy Helmut 2011-11-06 14:14
- WinNonlin’s BE wizard is known to be buggy yicaoting 2011-11-06 15:38
- WinNonlin’s BE wizard is known to be buggyHelmut 2011-11-06 16:53
- WinNonlin’s BE wizard is known to be buggy yicaoting 2011-11-06 17:12
- WinNonlin’s power? Helmut 2011-11-06 18:29
- WinNonlin’s BE wizard is known to be buggy yicaoting 2011-11-06 17:12
- WinNonlin’s BE wizard is known to be buggyHelmut 2011-11-06 16:53
- WinNonlin’s BE wizard is known to be buggy yicaoting 2011-11-06 15:38
- WinNonlin is lack of precision or? ElMaestro 2011-11-06 13:46
Ing. Helmut Schütz