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RegisterCmin and Tmin (WinNonlin) [Software]
posted by Helmut 
– Vienna, Austria, 2010-10-05 17:39 (5735 d 09:09 ago) – Posting: # 6000
Views: 7,197
Dear Ram,
I'm not sure whether I do understand your question. In a single dose study Cmin/tmin should be (by definition) <LLOQ/0. If not - your analytical method may be flawed, or the washout was too short (pre-dose concentrations in higher periods).
Yes, you can use the coding you gave in WinNonlin.
Can you give us an example (profile of one subject and WinNonlin's results)?
I'm not sure whether I do understand your question. In a single dose study Cmin/tmin should be (by definition) <LLOQ/0. If not - your analytical method may be flawed, or the washout was too short (pre-dose concentrations in higher periods).
Yes, you can use the coding you gave in WinNonlin.
❝ then obtained Cmin and Tmin are useful or not ??
Can you give us an example (profile of one subject and WinNonlin's results)?
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Cmin and Tmin (WinNonlin) kram 2010-10-05 15:25
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Cmin and Tmin (WinNonlin)Helmut 2010-10-05 15:39
- Cmin and Tmin (WinNonlin) kram 2010-10-06 12:02
- Endogenous compound? Helmut 2010-10-06 13:34
- Cmin and Tmin (WinNonlin) SDavis 2010-10-08 19:05
- Cmin and Tmin (WinNonlin) kram 2010-10-13 11:46
- Cmin and Tmin (WinNonlin) kram 2010-10-06 12:02
- Cmin and Tmin (WinNonlin)Helmut 2010-10-05 15:39
Ing. Helmut Schütz