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RegisterPower at 1.20 [Software]
posted by Helmut 
– Vienna, Austria, 2010-09-28 20:57 (5742 d 06:40 ago) – Posting: # 5948
Views: 7,126
Dear J. Detlor!
Yes, I’ve heard the term ‘forced BE’ also. If WeirdDude really talked about a ratio of 1.20 – well, let’s see whicht power we would get (24 subjects, usual settings,
):
Unless one has to deal with the ‘wonder-drug’ (CV 5.5 %), 24 subjects at a ratio of 1.20 are futile.
Exactly.
❝ I believe weirddude specified a 20% difference, which could mean an expected ratio of 120%. With enough subjects, the technical requirements for BE could be demonstated, but I believe this is what is referred to as 'forcing' BE. Some would say a ratio of 120% suggests the formulations are not bioequivalent.
Yes, I’ve heard the term ‘forced BE’ also. If WeirdDude really talked about a ratio of 1.20 – well, let’s see whicht power we would get (24 subjects, usual settings,
): CV% power
5.5 0.8017
10 0.3932
20 0.1704
30 0.1180Unless one has to deal with the ‘wonder-drug’ (CV 5.5 %), 24 subjects at a ratio of 1.20 are futile.
❝ To be specific, […]
Exactly.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Power Calculation of 2x2 crossover design (SAS) weirddude100 2010-09-21 18:13
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Power Calculation of 2x2 crossover design (SAS) jdetlor 2010-09-21 19:14
- Power at the limits of the acceptance range Helmut 2010-09-28 17:50
- Power at the limits of the acceptance range jdetlor 2010-09-28 18:37
- Power at 1.20Helmut 2010-09-28 18:57
- Power at 1.20 jdetlor 2010-09-28 20:28
- The Abuse of Power Helmut 2010-09-28 22:33
- Power at 1.20 jdetlor 2010-09-28 20:28
- Power at 1.20Helmut 2010-09-28 18:57
- Power at the limits of the acceptance range jdetlor 2010-09-28 18:37
- Power at the limits of the acceptance range Helmut 2010-09-28 17:50
- Power Calculation of 2x2 crossover design (SAS) d_labes 2010-09-27 08:51
- Power Calculation of 2x2 crossover design (SAS) jdetlor 2010-09-21 19:14
Ing. Helmut Schütz