Bioequivalence and Bioavailability Forum • Data imputation

Data imputation [Software]

posted by Ravi – India, 2010-04-26 08:35 (5893 d 13:01 ago) – Posting: # 5224
Views: 7,304

Dear HS,

Thanks for the detailed response.

We have outsourced this study to a CRO and their PK expert is using this approach i.e.

Exclude all the data form 96 hr onward when sampling was done upto 216 hr for both the periods and follow the usual procedure of NCA to generate the PK Parameters.

Please tell flaws in this procedure.

Thanks in advance.

—
Thanks & Regards
Ravi Pandey

Complete thread:

Missing value in WinNonlin Ravi 2010-04-24 06:16
- Data imputation Helmut 2010-04-24 16:21
  - Data imputationRavi 2010-04-26 06:35
    - Data imputation SDavis 2010-04-28 19:15
      - Data imputation Ravi 2010-04-29 06:36
        
        Data imputation /PHST reference #130355 SDavis 2010-04-29 09:42