To reinvent the wheel [Software]
Dear D. Labes!
Right!
I made this both satisfying and painful experience myself. First on a TI-59. When I started coding on a HP9000-workstation in 1981 there were only two PK-software packages for mainframes available (NONLIN and SAAM) and one for the WANG VS minicomputer. Nothing (!) for NCA and BE. So I had no choice anyhow. But it was great fun developing formulas for the trapezoidal rule and extrapolation for MRT∞ and VRT∞ and the like.
I wouldn’t miss it; learned a lot…
❝ You will get better control over what is going on if you roll your own.
Right!
❝ And all these Do nots were the reason why I took the profession of a wheel-reinventer some times ago. But also true, one has to spent a lot of time in reinventing the wheel from scratch.
I made this both satisfying and painful experience myself. First on a TI-59. When I started coding on a HP9000-workstation in 1981 there were only two PK-software packages for mainframes available (NONLIN and SAAM) and one for the WANG VS minicomputer. Nothing (!) for NCA and BE. So I had no choice anyhow. But it was great fun developing formulas for the trapezoidal rule and extrapolation for MRT∞ and VRT∞ and the like.

I wouldn’t miss it; learned a lot…
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- SAS or WinNonlin for Pharmacokinetics Nirali 2009-09-23 07:27
- SAS or WinNonlin for Pharmacokinetics Helmut 2009-09-23 13:16
- To SAS or not to SAS d_labes 2009-09-24 15:30
- To reinvent the wheelHelmut 2009-09-24 16:48
- To reinvent the wheel Nirali 2009-10-01 11:08
- To reinvent the wheelHelmut 2009-09-24 16:48
- To SAS or not to SAS d_labes 2009-09-24 15:30
- SAS or WinNonlin for Pharmacokinetics Helmut 2009-09-23 13:16