Bioequivalence and Bioavailability Forum

Hello,

I'm new at BA/BE studies and I don't understand very well how to analyze a crossover experiment with R or SAS.

I'm trying to replicate the results I've read in a book (Design and analysis of bioavailability and bioequivalence studies): a complete example is proposed in section 3.6, data is p.73 and the classic ANOVA table I want to obtain is p.78.

I would like to know how I can obtain such an ANOVA table with R or SAS, with inter- and intra- source of variations separated.

I don't manage to write properly the model, in order to make SAS or R understand that each subject has two measures, and that some factors have to be tested between subject, and others within subjects.

Do you a have a document, or a code "ready to use" which could help me to replicate the results of the book ?

Thanks !

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Edit: Subject line changed. [Helmut]