Deconvolution IS possible in WinNonlin [Software]
Small correction to Helmut's comment
WinNonlin Professional on it's own can do Deconvolution (since 3.1), primarily intended for use with a UIR derived from an IV reference. It is a constrained deconvolution method that produces a smooth estimate of the input rate which is constrained to be non-negative. The degree of smoothness may specified by the user.
However as Helmut mentioned, for convolution among other functions, Pharsight has built an 'add on', the IVIVC toolkit, that supports your workflows while building, validating and predicting from your correlation model. You can find out more about this module by looking at some of the past event recordings, see below.
Best regards,
Simon.
IVIVC Toolkit for WinNonlin: Product Introduction & Demonstration http://pharsight.com/events/eventsonline_archive.php#replay_009
IVIVC Applications and Case Studies
http://pharsight.com/events/eventsonline_archive.php#replay_015
WinNonlin Professional on it's own can do Deconvolution (since 3.1), primarily intended for use with a UIR derived from an IV reference. It is a constrained deconvolution method that produces a smooth estimate of the input rate which is constrained to be non-negative. The degree of smoothness may specified by the user.
However as Helmut mentioned, for convolution among other functions, Pharsight has built an 'add on', the IVIVC toolkit, that supports your workflows while building, validating and predicting from your correlation model. You can find out more about this module by looking at some of the past event recordings, see below.
Best regards,
Simon.
IVIVC Toolkit for WinNonlin: Product Introduction & Demonstration http://pharsight.com/events/eventsonline_archive.php#replay_009
IVIVC Applications and Case Studies
http://pharsight.com/events/eventsonline_archive.php#replay_015
—
Simon
Senior Scientific Trainer, Certara™
[link=https://www.youtube.com/watch?v=xX-yCO5Rzag[/link]
https://www.certarauniversity.com/dashboard
https://support.certara.com/forums/
Simon
Senior Scientific Trainer, Certara™
[link=https://www.youtube.com/watch?v=xX-yCO5Rzag[/link]
https://www.certarauniversity.com/dashboard
https://support.certara.com/forums/
Complete thread:
- Deconvolution thong 2009-02-06 16:16
- Deconvolution Helmut 2009-02-06 16:39
- Deconvolution IS possible in WinNonlinSDavis 2009-02-06 23:35