Bioequivalence and Bioavailability Forum

Dear D.Labes,

Thank you for your reply.

For the below data, I got the R² values as follows
    X    |  Y
  50.020 | 0.012
  75.030 | 0.026
 100.040 | 0.035
 150.059 | 0.061
 175.069 | 0.073
 200.079 | 0.086
 300.119 | 0.134
 500.198 | 0.222
 750.296 | 0.364
1000.395 | 0.477
1100.435 | 0.618
1200.474 | 0.624

In Analyst Software
For Linear equation,
1) Using weighting index=1/x, R² = 0.9956
2) Using weighting index=1/x², R² = 0.9875
3) For Quadratic equation using weighting index=1/x, R²= 0.9984

In SAS Analyst Using Simple Regression
For Linear equation,
1) Using weighting index =1/x, R²= 0.5069
2) Using weighting index =1/x², R² = 0.2734
3) For quadratic equation using weighting index 1/x, R² = 0.7925

example for linear equation using weighting index 1/x² SAS code is
*** Simple Regression ***;                                                   
 options pageno=1;                                                             
 proc reg data=Work.Sas;                                                       
    model Y = B;                                                           
run;                                                                         
quit;
Note: B=1/x²

Now my questions are,
1) Why my SAS R² values are different compared to the Analyst R² values?
2) Is there any mistake in my calculation?

Thanks in advance

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