Bioequivalence and Bioavailability Forum

is zero positive? [Software]

posted by mittyri  – Russia, 2018-07-14 01:31 (2893 d 16:08 ago) – Posting: # 19059
Views: 10,564

Hi Babe_Ruth,

❝ However, when I set BQL to 0, it uses a linear-trapezoidal rule: (Clast + 0)*(T16 - Tlast)

well... let me try to cite it again
If a start or end time falls within the range of the data but does not coincide with an observed data point, then a linear or logarithmic interpolation is done to estimate the corresponding Y, according to the AUC Calculation method selected in the NCA Options. (See “NCA Options tab” on page 42.) Note that logarithmic interpolation is overridden by linear interpolation in the case of a non-positive endpoint.
A question:
is 0 a positive endpoint?

PS: nice to see you are using good oldie 6.3 (decennary next year)

Complete thread:

• WNL Calculation of partial areas > tlast with BQL= 0 rule Babe_Ruth 2018-07-13 21:36 
  • WNL Calculation of partial areas > tlast with BQL= 0 rule ElMaestro 2018-07-13 22:25
  • BQL = 0: bad rule Helmut 2018-07-13 23:28
    • BQL = 0: bad rule Babe_Ruth 2018-07-16 15:02
      • BQL = 0: bad rule Helmut 2018-07-16 16:02
        • BQL = 0: bad rule martin 2018-07-16 20:03
    • BQL = 0: bad rule martin 2018-07-16 20:43
  • is zero positive?mittyri 2018-07-13 23:31
    • sgn(0) = 0 Helmut 2018-07-13 23:58
    • is zero positive? Babe_Ruth 2018-07-16 14:49