Bioequivalence and Bioavailability Forum • Least square mean

Least square mean [Software]

posted by JPL – Vienna, 2008-06-03 11:10 (6183 d 12:13 ago) – Posting: # 1900
Views: 8,750

Dear Yu,

in fact Least Square Means (LSMeans) are not an issue of X-over studies only but of unbalanced data. For the balanced case LSMeans and Means agree, for the unbalanced case, LSMeans account for the size of the group the LSMeans is determined of. Find a basic example here: http://www.uidaho.edu/ag/statprog/sas/workshops/glm/lsmeans.htm

Regards,
JPL

Complete thread:

Mean calculation method in unbalanced cross-over study yckim 2008-05-27 15:04
- EquivTest v1 / v2 / PK Helmut 2008-05-27 15:41
  - EquivTest v1 / v2 / PK yckim 2008-05-28 01:39
    - Weighted mean Helmut 2008-05-28 11:55
      - Least square mean d_labes 2008-05-28 16:35
        
        Least square mean yckim 2008-06-03 07:46
        
        Least square meanJPL 2008-06-03 09:10
        
        Least square mean vish14184 2008-06-04 06:54
        
        Least square mean JPL 2008-06-04 08:44