Bioequivalence and Bioavailability Forum • Least square mean

Least square mean [Software]

posted by yckim – 2008-06-03 09:46 (6183 d 16:18 ago) – Posting: # 1899
Views: 8,591

Dear HS and d_labes

There seems to be opinions that 'mean of the means' (least square mean?) is right in cross-over study. Even Equiv 2.0 use the term of 'least square mean'. In addition, many texts on statistics use the 'mean of the means' formula. Please help me clearly understand which method is right and the rationale.

Best regards,

YCKim

Complete thread:

Mean calculation method in unbalanced cross-over study yckim 2008-05-27 15:04
- EquivTest v1 / v2 / PK Helmut 2008-05-27 15:41
  - EquivTest v1 / v2 / PK yckim 2008-05-28 01:39
    - Weighted mean Helmut 2008-05-28 11:55
      - Least square mean d_labes 2008-05-28 16:35
        
        Least square meanyckim 2008-06-03 07:46
        
        Least square mean JPL 2008-06-03 09:10
        
        Least square mean vish14184 2008-06-04 06:54
        
        Least square mean JPL 2008-06-04 08:44