Bioequivalence and Bioavailability Forum • EquivTest v1 / v2 / PK

EquivTest v1 / v2 / PK [Software]

posted by yckim – 2008-05-28 03:39 (6597 d 04:18 ago) – Posting: # 1876
Views: 11,060

Dear HS

Thank you very much for your reply!
However, I am a little confused about followings.

❝ In the case of an unbalanced study (n1 # n2) only the latter.

❝ In technical terms, the second one is wrong for unbalanced studies; the bias will depend on both the overall size of the study (n1+n2) and the degree of unbalance (ratio of n1/n2).

You said the method of equivtest 2.0 is right in the former while it is wrong in the latter. Please clarify it.

Thank you.

Best regards,

Yu Chul Kim

Edit: Standard quotes restored. [Helmut]

Complete thread:

Mean calculation method in unbalanced cross-over study yckim 2008-05-27 15:04
- EquivTest v1 / v2 / PK Helmut 2008-05-27 15:41
  - EquivTest v1 / v2 / PKyckim 2008-05-28 01:39
    - Weighted mean Helmut 2008-05-28 11:55
      - Least square mean d_labes 2008-05-28 16:35
        
        Least square mean yckim 2008-06-03 07:46
        
        Least square mean JPL 2008-06-03 09:10
        
        Least square mean vish14184 2008-06-04 06:54
        
        Least square mean JPL 2008-06-04 08:44