Bioequivalence and Bioavailability Forum • Emax and ED50: NLME

Emax and ED50: NLME [Software]

posted by Helmut – Vienna, Austria, 2015-12-30 15:56 (3399 d 18:10 ago) – Posting: # 15781
Views: 18,013

Hi G.C.,

❝ Thanks for your detailed response.

Welcome.

❝ We also get same value using WinNonlin.

Are you satisfied now or even more worried? Why didn’t you bother to answer any of my questions? I still think that the model is wrong. If I compare FDA’s results to the others its relative error (bias, if you want) is +22.7% for E_max and +65.8% for ED₅₀. Now what?

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Helmut Schütz

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Complete thread:

Emax and ED50: NLME gcpatel126 2015-12-09 18:08
- Emax and ED50: NLME Helmut 2015-12-10 02:09
  - Emax and ED50: NLME gcpatel126 2015-12-10 17:34
    - Emax and ED50: NLME SDavis 2015-12-15 11:50
      - Emax and ED50: NLME gcpatel126 2015-12-29 15:49
        
        Emax and ED50: NLME Helmut 2015-12-29 17:46
        
        Emax and ED50: NLME gcpatel126 2015-12-29 18:04
        
        Emax and ED50: NLME Helmut 2015-12-29 19:36
        
        Emax and ED50: NLME gcpatel126 2015-12-30 14:43
        
        Emax and ED50: NLMEHelmut 2015-12-30 14:56
        
        Emax and ED50: NLME gcpatel126 2015-12-30 15:19
        
        Validation? Helmut 2015-12-30 16:02
        
        Validation? gcpatel126 2015-12-30 17:47
        
        Validation? Helmut 2015-12-30 21:15
        
        Validation? gcpatel126 2015-12-31 07:06
        
        Validation? gcpatel126 2016-01-11 14:54
        
        EOD Helmut 2016-01-11 22:13