Bioequivalence and Bioavailability Forum

Ct curves from single dose to predict multiple dose [Software]

posted by d_labes – Berlin, Germany, 2015-10-08 21:57 (3917 d 01:34 ago) – Posting: # 15533
Views: 18,257

Dear all,

I have some concentration time curves after single dose application.

Now I have the task to predict from these curves the concentration time course after multiple dosing, assuming lineare kinetics.

Does anybody knows any software to accomplish this task or has some code in f.i. R for superposition the concentration time curves after single dose application?

Best would be without some compartment model fit (NCA).
Second best with using some compartment model.

Any help would be greatly appreciated.

—
Regards,

Detlew

Complete thread:

Ct curves from single dose to predict multiple dosed_labes 2015-10-08 19:57
- Phoenix/WinNonlin: NonParametric Superposition Helmut 2015-10-08 21:02
- Ct curves from single dose to predict multiple dose yjlee168 2015-10-09 06:39
  - Software for superposition d_labes 2015-10-09 08:46
    - PK-Xpress: impressions Helmut 2015-10-09 14:23
      - PK-Xpress: impressions d_labes 2015-10-09 20:23
        
        OT: list limbo and (X)HTML Helmut 2015-10-10 01:06
        
        OT: list limbo and (X)HTML Ohlbe 2015-10-10 23:15
        
        OT: list limbo and (X)HTML Helmut 2015-10-11 00:01
        
        OT: list limbo and (X)HTML d_labes 2015-10-11 14:55
  - JGuiB Helmut 2015-10-09 13:16

Ct curves from single dose to pre­dict multiple dose [Software]

Complete thread:

Ct curves from single dose to predict multiple dose [Software]