Bioequivalence and Bioavailability Forum • Star Trek: The Next Generation

Star Trek: The Next Generation [Software]

posted by yjlee168 – Kaohsiung, Taiwan, 2014-10-09 13:06 (4272 d 06:35 ago) – Posting: # 13675
Views: 42,994

Dear Helmut,

Have you ever tried to add/change options of MAXITER (default is only 50; may consider to increase this value) and / or MAXFUNC (default is 150) with PROC MIXED when getting convergence failure for ABE? I did that with lme() in bear recently for dataset that failed to converge using the default number of iterations. It solved the problem of convergence failure. The function optimization of PROC MIXED is the Newton-Raphson algorithm. I don't know if it works or not with PROC MIXED.

❝ [...]

❝ • FDA

❝ • ABE

❝ • FA0(2): according to the guidance; sometimes a warning, sometimes no convergence

❝ • CSH: suggested as an alternative in the guidance; fails to converge sometimes as well [...]

❝ • FA0(1): no problems with convergence in all datasets we have tested so far [...]

—
All the best,
-- Yung-jin Lee
bear v2.9.6:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

reference dataset elba.romero 2013-07-02 05:08
- Public datasets Helmut 2013-07-02 15:44
  - Public datasets yjlee168 2013-07-03 03:10
    - Public datasets elba.romero 2013-07-03 05:19
      - Public datasets yjlee168 2013-07-03 13:11
        
        Challenging data sets Helmut 2013-07-03 16:32
        
        Fantastic idea? ⇒ Challenging data sets yjlee168 2013-07-04 08:06
        
        Fantastic idea! Helmut 2013-07-04 13:18
    - NIST; cross-validation Helmut 2013-07-03 14:28
      - NIST; cross-validation yjlee168 2013-07-03 23:47
        
        NIST; cross-validation Helmut 2013-07-04 00:45
  - Public datasets elba.romero 2013-07-03 05:10
- Eight Reference Datasets (2×2×2 ☑) Helmut 2014-10-06 02:24
  - What??? ElMaestro 2014-10-06 13:20
    - What??? Helmut 2014-10-06 17:08
      - What??? ElMaestro 2014-10-06 17:31
        
        What the heck‽ Helmut 2014-10-06 19:05
  - link of electronic supplement material? yjlee168 2014-10-07 09:53
    - link of electronic supplement material? nobody 2014-10-07 10:59
      - Thanks! yjlee168 2014-10-07 11:35
        
        Thanks! nobody 2014-10-07 11:44
        
        Direct links & hint Helmut 2014-10-07 13:54
    - Replicated designs are relevant, too ElMaestro 2014-10-07 12:36
      - Replicated designs are relevant, too yjlee168 2014-10-07 13:00
        
        RSABE: SAS and PHX/WNL only? Helmut 2014-10-07 14:47
        
        for the future? yjlee168 2014-10-08 10:05
        
        Star Trek: The Next Generation Helmut 2014-10-09 00:26
        
        Star Trek: The Next Generation d_labes 2014-10-09 08:09
        Star Trek: The Next Generation nobody 2014-10-09 08:23
        Star Trek: The Next Generationyjlee168 2014-10-09 11:06
        
        Some comments ElMaestro 2014-10-09 11:52
        
        Some comments yjlee168 2014-10-09 12:18
        
        Proc MIXED - start value d_labes 2014-10-10 08:35
        
        Proc MIXED - start value ElMaestro 2014-10-10 11:44
        Proc MIXED - start value yjlee168 2014-10-11 21:09
        
        Proc MIXED - start value ElMaestro 2014-10-11 21:18
        
        Optimizer settings Helmut 2014-10-09 14:08
        
        Optimizer settings nobody 2014-10-09 15:32
        Optimizer settings yjlee168 2014-10-09 18:14
        
        FDA’s model… Helmut 2014-10-09 18:34
  - Just received a letter… Helmut 2014-11-03 14:54
  - 11 Reference Datasets (2-group parallel ☑) Helmut 2014-12-09 15:51