Correlation / IVIVC Wizard / WinNonlin [Software]

posted by Samaya B – India, 2014-07-31 14:48 (4341 d 07:49 ago) – Posting: # 13324
Views: 8,647

Dear All,
Good afternoon!

I was performing IVIVC using IVIVC Wizard_ WinNolin for the first time using 3 different Test formulation with slow, medium and fast release rate) and got stuck in third tab (Correlation). It would be very helpful if anyone can explain exact meaning of following correlation models and which correlation model is to be chosen while performing IVIVC?

2. Fabs = AbsScale * Diss (Tscale * Tvivo)
3. Fabs = AbsScale * Diss (Tscale * Tvivo - Tshift)
4. Fabs = AbsScale * (Diss (Tscale * Tvivo - Tshift) – AbsBase)


Kinldy advice!

Thank you!
Regards,
Samaya


Edit: I added numbers to the models. You forgot to mention the first one:
  1. Fabs = Diss (Tvivo)
[Helmut]

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