Bioequivalence and Bioavailability Forum

WNL, time deviations [Software]

posted by Beholder  – Russia, 2014-03-25 07:23 (4454 d 14:52 ago) – Posting: # 12700
Views: 14,641

Dear all,

Please could you help me in adjusting nominal time of blood sampling to actual time of blood sampling in WNL for BE study. I will try to explain.

If we have nominal time, for example, 1.25 h, 1.50 h, 1.75 h and 1 minute time deviation on 1.50 h time point for 1 volunteer from 30 then we have following actual time for that volunteer as 1.25 h, ~1.517 h, 1.75 h. After this I get following average graph:


Then you see that I got 2 points (1.50 h for 29 volunteers and 1.517 h for 1 volunteer) on one time interval (see the red circle). How could I handle it?

Thank you in advance.

Complete thread:

• WNL, time deviationsBeholder 2014-03-25 06:23 
  • Use nominal times fno 2014-03-25 09:47
    • Use nominal times Beholder 2014-03-27 07:50
      • Data binning Helmut 2014-03-27 13:47
        • Data binning Beholder 2014-03-28 08:08
        • Mean concentration curves – which mean #666 d_labes 2014-03-28 11:30
    • Use nominal times AngusMcLean 2014-03-29 13:06
      • Use nominal times mittyri 2014-03-29 14:45
    • Use nominal times mittyri 2014-03-31 20:31
      • Use nominal times fno 2014-04-01 17:48
        • Use nominal times Beholder 2014-04-02 08:23
          • Use nominal times fno 2014-04-02 17:16
        • SOPitis? Helmut 2014-04-02 11:57
          • SOPitis? fno 2014-04-04 09:49
  • WNL, time deviations SDavis 2014-04-24 15:10