Bioequivalence and Bioavailability Forum

Hi Helmut,

Thank you so much for the reply

❝ 3. Generally yes. But there is a case where you would drop the subject even if only one period is missing: Two test available and the reference missing.

ok right, can't take BE in this case too.

❝ Homework: Fully replicate three-period design (RTR|RTR).

In this case i.e. Partially replicate design, I would consider that subject, In which their is 1(T) & 1 (R) available and would not consider the Subjects with both (R)or with just 1(T) or 1 (R).

Thanks & Regards