Bioequivalence and Bioavailability Forum • MSE tables

MSE tables [Software]

posted by AngusMcLean – USA, 2014-02-24 17:56 (4074 d 19:57 ago) – Posting: # 12480
Views: 8,849

Helmut: I will ask them; it really should be there. I looked up your reference to intercept (see below in the users guide)

For non-replicated crossover designs, the default model is as follows.
Fixed effects model is:

❝ Dependent variable = Intercept + Sequence + Formulation + Period

I know that the dependent variable say AUC and we have a regression relationship (or it a multiple regression) relating it to the Sequence, Formulation and period. Is this the calculation of the AUC of one individual in a given sequence, given period and treated with a given formulation?

How is it that the Sequence, Formulation and period are obtained in terms of AUC. Does this relate to matrix algebra? In general and in simple terms how should we think of that equation.

Angus

Complete thread:

Phoenix WinNonlin ANOVA AngusMcLean 2014-02-24 00:07
- Intercept Helmut 2014-02-24 00:51
  - Intercept AngusMcLean 2014-02-24 15:08
    - MSE tables Helmut 2014-02-24 15:58
      - MSE tablesAngusMcLean 2014-02-24 16:56
        
        MSE tables ElMaestro 2014-02-24 17:26
        
        MSE tables AngusMcLean 2014-02-24 18:02
        
        MSE tables ElMaestro 2014-02-24 18:17
        
        MSE tables AngusMcLean 2014-02-24 19:56
        
        MSE tables ElMaestro 2014-02-24 23:58
        
        MSE tables AngusMcLean 2014-02-25 01:25