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RegisterIntrasubject Variance in WinNonlin [Software]
Hi all,
Greetings!
I've had done a Partially Replicate BE Study. After running the WinNonlin software for the Partially Replicate study I couldn't get Intrasubject variability directly (Unlike Fully Replicate and Cross over studies) but had done manual calculations on the available Var(Residual) by using the formula:
Intrasubject CV = sqrt(exp(Residual_Variance) - 1). The same problem had cropped up for Three way crossover study as well.
Kindly guide me how can I get the Intrasubject CV value directly from the software itself or can I put whole formula somewhere to get the CV.
Thanks & Regards
Anu
Greetings!
I've had done a Partially Replicate BE Study. After running the WinNonlin software for the Partially Replicate study I couldn't get Intrasubject variability directly (Unlike Fully Replicate and Cross over studies) but had done manual calculations on the available Var(Residual) by using the formula:
Intrasubject CV = sqrt(exp(Residual_Variance) - 1). The same problem had cropped up for Three way crossover study as well.
Kindly guide me how can I get the Intrasubject CV value directly from the software itself or can I put whole formula somewhere to get the CV.
Thanks & Regards
Anu
Complete thread:
- Intrasubject Variance in WinNonlinAnu 2013-07-29 13:04
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- CVintra: method Helmut 2013-07-30 13:51
- CVintra: method Anu 2013-08-02 10:49
- CVintra: method Helmut 2013-08-02 14:24
- CVintra: method BRN 2014-02-04 18:00
- Full or crippled model Helmut 2014-02-05 14:41
- Full or crippled model BRN 2014-02-06 08:38
- Widening the acceptance range Helmut 2014-02-06 14:42
- Full or crippled model BRN 2014-02-06 08:38
- Full or crippled model Helmut 2014-02-05 14:41
- CVintra: method Anu 2013-08-02 10:49
- CVintra: method Helmut 2013-07-30 13:51
Ing. Helmut Schütz