What software can change alpha to evaluate BE? [Software]
Dear all,
We did a typical 2×2 cross-over study for BE study in 23 subjecct. The results (by WinNonlin 6.3) showed the power<0.8 and also not BE (in the "Average Bioequivalence" table). We want to try to evaluate the data by alpha =0.0294 (based on Potvin's Method C). But I did not find the option in WinNonlin. I wonder if anyone could tell me which software can do this? I think it sound a bit stupid, but I really hope someone could give me a favor.
What I have and know: pharmacy background and have WinNonlin (learn on my own by the Guide), R (basic skill, but I hear the R package bear and PowerTost in the forum
) and NONMEM.
Thanks in advance!
We did a typical 2×2 cross-over study for BE study in 23 subjecct. The results (by WinNonlin 6.3) showed the power<0.8 and also not BE (in the "Average Bioequivalence" table). We want to try to evaluate the data by alpha =0.0294 (based on Potvin's Method C). But I did not find the option in WinNonlin. I wonder if anyone could tell me which software can do this? I think it sound a bit stupid, but I really hope someone could give me a favor.
What I have and know: pharmacy background and have WinNonlin (learn on my own by the Guide), R (basic skill, but I hear the R package bear and PowerTost in the forum

Thanks in advance!
—
Best regards,
Xipei
China
Best regards,
Xipei
China
Complete thread:
- What software can change alpha to evaluate BE?wxp 2013-03-29 09:31
- What software can change alpha to evaluate BE? ElMaestro 2013-03-29 10:38
- What software can change alpha to evaluate BE? wxp 2013-04-02 10:06
- What software can change alpha to evaluate BE? krishna 2013-03-29 11:32
- What software can change alpha to evaluate BE? wxp 2013-04-02 10:03
- Phoenix settings for Potvin B/C Helmut 2013-03-29 11:46
- Phoenix settings for Potvin B/C wxp 2013-04-02 10:20
- What software can change alpha to evaluate BE? ElMaestro 2013-03-29 10:38