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Registerf2 similarity factor metric [Dissolution / BCS / IVIVC]
Hi Sundar,
what are you trying to ask? Convert to concentration? Can't you calculate percent dissolved and the compute the cumulative????
John
❝ f2 = 50*Log{1+1/N[SUM(Rt-Tt)2]}-0.5*100
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❝ where, Rt and Tt are the cumulative percentage dissolved at each of the selected n time points of the reference and test product, respectively.
❝
❝ Here, my doubt is in place of time, shall we use change in concentration where there is no time specific involvement.
what are you trying to ask? Convert to concentration? Can't you calculate percent dissolved and the compute the cumulative????
John
Complete thread:
- f2 similarity factor metric msmnainar 2013-01-30 07:20
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- Please clarify Helmut 2013-02-01 14:30
- f2 similarity factor metricjag009 2013-02-01 20:39
- f2 similarity factor metric msmnainar 2013-02-04 06:21
- f2 similarity factor metric Oiinkie 2013-02-04 17:14
- f2 similarity factor metric msmnainar 2013-02-07 08:07
- f2 similarity factor metric Oiinkie 2013-02-04 17:14
- f2 similarity factor metric msmnainar 2013-02-04 06:21
Ing. Helmut Schütz