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RegisterBiphasic IVIVC Model [Dissolution / BCS / IVIVC]
posted by SDavis 
– UK, 2012-11-19 09:27 (4970 d 04:45 ago) – Posting: # 9548
Views: 6,473
John, I would build my model on the single entity/whole capsule; I think this is fairly common formulation design and I've certainly seen IVIVCs successfully constructed around these to aid development. I don't know if anyone has tried to apply for a biowaiver but I will ask our consulting group
Simon
PS found an example; Chittenden J. In Vitro / In Vivo Correlation (IVIVC) Development for a model compound with release rate specific bioavailability. [poster abstract T2037].
Presented at: AAPS Annual Meeting; November 11-15; San Diego, California. I have this in PDF but not sure how to attach here
Simon
PS found an example; Chittenden J. In Vitro / In Vivo Correlation (IVIVC) Development for a model compound with release rate specific bioavailability. [poster abstract T2037].
Presented at: AAPS Annual Meeting; November 11-15; San Diego, California. I have this in PDF but not sure how to attach here
—
Simon
Senior Scientific Trainer, Certara™
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Simon
Senior Scientific Trainer, Certara™
[link=https://www.youtube.com/watch?v=xX-yCO5Rzag[/link]
https://www.certarauniversity.com/dashboard
https://support.certara.com/forums/
Complete thread:
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- Biphasic IVIVC Model Helmut 2012-11-08 00:27
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- Biphasic IVIVC Model Helmut 2012-11-19 15:24
- Biphasic IVIVC Model jag009 2012-11-20 17:07
- That's why! ElMaestro 2012-11-20 17:19
- Biphasic IVIVC Model jag009 2012-11-20 17:07
- Biphasic IVIVC Model Helmut 2012-11-19 15:24
Ing. Helmut Schütz