Polynomial UIR [Dissolution / BCS / IVIVC]

posted by Harish Kaushik – India, 2012-05-21 12:52 (5140 d 13:26 ago) – Posting: # 8592
Views: 4,686

Hello HS,
Iam novice in the field of IVIVC and Iam trying to understand the background of using Polynomial UIR function for deconvolution from PO &IV Bolus data.
What is the significance of increasing exponentials from 2(bi),3(tri),... etc for predicting the absorption profile of the drug

Please can you elaborate me !!

Regards
Harish Kaushik

Complete thread:

UA Flag
Activity
 Admin contact
23,654 posts in 4,992 threads, 1,571 registered users;
149 visitors (0 registered, 149 guests [including 11 identified bots]).
Forum time: 02:19 CEST (Europe/Vienna)

“Data! Data! Data!” he cried impatiently.
“I can’t make bricks without clay!”    Arthur Conan Doyle

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5