Bioequivalence and Bioavailability Forum

Thanks for promt reply.

But in pivotal study reference drug also behave lower side as compare to pilot study.

Dissolution we check the rate of drug dissolve/release from formulation to solution. If drug having limited permeability then both test and reference drug affect not only single one.

---

Edit: Full quote removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! Added last paragraph from another post. Don’t start a new post if you want to add something; edit your original post instead. [Helmut]