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RegisterF1 and F2 values [Dissolution / BCS / IVIVC]
posted by Helmut 
– Vienna, Austria, 2010-08-03 17:36 (5807 d 20:27 ago) – Posting: # 5710
Views: 4,137
Dear Kishor!
See this post and the given references.
No. Any in vitro method is just a surrogate of in vivo bioequivalence. f2 <50 does not invalidate proven BE.
I don't get your point. Can you please try to reword it?
❝ Can any one tell me basics of F1 and F2 values and its significance in BE study?
See this post and the given references.
❝ Is it compulsory that F2 values should be matching to reference and test formulation?
No. Any in vitro method is just a surrogate of in vivo bioequivalence. f2 <50 does not invalidate proven BE.
❝ What will be the assay range for Reference & Test?
I don't get your point. Can you please try to reword it?
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Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
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Complete thread:
- F1 and F2 values kishor 2010-08-03 06:12
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- F1 and F2 valuesHelmut 2010-08-03 15:36
Ing. Helmut Schütz