AUC correction of absorption profiles [Dissolution / BCS / IVIVC]
Dear group,
Say, If I have a BE study data with AUC "100 ng·hr/ml" for treatment A and "90 ng·hr/ml" for treatment B. While generating absorption profiles (wagnor nelson method) for A and B, I get a overlaping profiles.
The question is do I need to correct the profile of B with AUCs ratio (ie., 0.9) for further utility?
Thanks
Ashok
Say, If I have a BE study data with AUC "100 ng·hr/ml" for treatment A and "90 ng·hr/ml" for treatment B. While generating absorption profiles (wagnor nelson method) for A and B, I get a overlaping profiles.
The question is do I need to correct the profile of B with AUCs ratio (ie., 0.9) for further utility?
Thanks
Ashok
Complete thread:
- AUC correction of absorption profilesyashokrajv 2009-08-22 13:51
- AUC correction of absorption profiles yashokrajv 2009-09-08 13:28
- AUC correction of absorption profiles SDavis 2009-09-09 08:54
- AUC correction of absorption profiles yashokrajv 2009-09-08 13:28
