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RegisterDeconvolution [Dissolution / BCS / IVIVC]
Dear All,
I would like to know why in a deconvolution procedure (Wagner Nelson or Loo Riegelman) the 100% of fraction absorbed is not achieved in Tmax? For example, plasma concentration versus time figure with Tmax = 3h and fraction absorbed versus time figure with 100% absorved in 8h (only 60 - 70% in 3h (Tmax).
Thank you in advance.
Daniel Rossi de Campos
Brazil
I would like to know why in a deconvolution procedure (Wagner Nelson or Loo Riegelman) the 100% of fraction absorbed is not achieved in Tmax? For example, plasma concentration versus time figure with Tmax = 3h and fraction absorbed versus time figure with 100% absorved in 8h (only 60 - 70% in 3h (Tmax).
Thank you in advance.
Daniel Rossi de Campos
Brazil
Complete thread:
- Deconvolutiondrcampos 2008-09-09 03:34
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Deconvolution Ohlbe 2008-09-09 17:22
- Deconvolution drcampos 2008-09-09 21:14
- Deconvolution Ohlbe 2008-09-09 17:22
Ing. Helmut Schütz