Bioequivalence and Bioavailability Forum • EMA: Mahalanobis distance is dead...

EMA: Mahalanobis distance is dead... [Dissolution / BCS / IVIVC]

posted by ElMaestro – Denmark, 2018-11-09 20:12 (2763 d 11:58 ago) – Posting: # 19559
Views: 12,443

Thanks Hötzi,

I applaud that move.
Bootstrapping has enormous potential, not just for dissolution. Sometimes the idea behind bootstrapping to me appears so simple and naïve that I am thinking it must be wrong :-|

. Especially considering how often we complicate simple issues with fancy maths. :-D

So due to this step in the right direction I'll put flags on the table tonight and celebrate. :-)

—
Pass or fail!
ElMaestro

Complete thread:

EMA: Mahalanobis distance is dead... Helmut 2018-11-09 18:01
- EMA: Mahalanobis distance is dead...ElMaestro 2018-11-09 19:12
  - Is ƒ2 dead as well – always bootstrapping? Helmut 2019-10-06 15:27
    - Is ƒ2 dead as well – always bootstrapping? ElMaestro 2019-10-06 17:54
      - Ahem – number of units? Helmut 2019-10-06 18:14
        
        Ahem – number of units? ElMaestro 2019-10-06 22:45
        
        Ahem – number of units? wienui 2019-10-07 19:11
        Ahem – number of units? elba.romero 2021-10-28 00:08
        
        Ahem – number of units - ICH M9 Relaxation 2021-10-28 16:20