f2 comparison [Dissolution / BCS / IVIVC]

posted by wienui  – Germany/Oman, 2018-04-10 19:39 (2990 d 13:29 ago) – Posting: # 18663
Views: 7,134

(edited on 2018-04-11 06:11)

Hi John,
Yes you need to calculate the f2 (as you cann't prove the release at 15 min was ≥ 85%.) for the above given 3 dissolution time points and don't include anymore time points.
What about the CV% or RSD% for the 10min and the other time points? otherwise bootstrapping is recommended.
Best regards,
Osama


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

Cheers,
Osama

Complete thread:

UA Flag
Activity
 Admin contact
23,654 posts in 4,992 threads, 1,571 registered users;
170 visitors (0 registered, 170 guests [including 15 identified bots]).
Forum time: 09:08 CEST (Europe/Vienna)

“Data! Data! Data!” he cried impatiently.
“I can’t make bricks without clay!”    Arthur Conan Doyle

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5