What is the role of caffeine in bioequivalence studies? [Dissolution / BCS / IVIVC]

posted by Mauricio Sampaio  – Brazil, 2016-05-18 19:43 (3679 d 06:38 ago) – Posting: # 16327
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Hello for all!

I would like to confirm an information with experts in BCS....
Caffeine is a reference standard to determine the biopharmaceutical classification of other drugs according with solubility and permeability?

If yes, this is a possible reason thcat support the FDA to classify caffeine as an effective substance which there are no bioequivalence problems?

I really appreciate any colaboration ( with references, if is possible) , because I would like to understand why is not need to measure caffeine in bioequivalence studies.

Best regards.

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