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RegisterDrug degrades in pH4.5 and HCl [Dissolution / BCS / IVIVC]
Dear Ken
Even if the drug degrades in pH4.5 and pH1.2 (0.1 HCl) the comparative dissolution profiles obtained in these media will give you some information on your formulation in comparison to the reference. Degradation is substance specific whereas disintegration and solubility of your API in your product are formulation specific.
Kind regards
Dr_Dan
Even if the drug degrades in pH4.5 and pH1.2 (0.1 HCl) the comparative dissolution profiles obtained in these media will give you some information on your formulation in comparison to the reference. Degradation is substance specific whereas disintegration and solubility of your API in your product are formulation specific.
Kind regards
Dr_Dan
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Kind regards and have a nice day
Dr_Dan
Kind regards and have a nice day
Dr_Dan
Complete thread:
- Drug degrades in pH4.5 and HCl Ken Peh 2014-04-22 10:48
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Drug degrades in pH4.5 and HClDr_Dan 2014-04-22 12:42
- Drug degrades in pH4.5 and HCl Ken Peh 2014-04-27 20:43
- Drug degrades… Helmut 2014-05-26 19:18
- Drug degrades in pH4.5 and HClDr_Dan 2014-04-22 12:42
Ing. Helmut Schütz