Bioequivalence and Bioavailability Forum • IVIVC calculations

IVIVC calculations [Dissolution / BCS / IVIVC]

posted by mahendra – US, 2013-10-24 18:10 (4267 d 18:20 ago) – Posting: # 11753
Views: 46,100

Hi
I am working in analytical method development for Pharmaceutical company.

I want to just learn how to do IVIVC comparison.

For a Batch of drug product:

for Invitro: data: % drug dissolved in 15 min, 30 min, 45 min intervals.
For invivo: What data do i need ? Like AUC, Cmax etc.

I am unbale to see examples on this. Colud any one help me to learn this? Its my interest.

I have Minitab 16: is it capble to IVIVC?

I see recently in a post that mentioned IVIVC is possible in R software? I dont know about R software and i have not used it? Is it simple to run IVIVC in R to learn?

I want to see practically how IVIVC data give the information for next development?

Thanks in advance

Complete thread:

IVIVC calculationsmahendra 2013-10-24 16:10
- IVIVC calculations yjlee168 2013-10-24 19:22
  - IVIVC calculations mahendra 2013-10-24 19:45
    - IVIVC calculations yjlee168 2013-10-24 22:21
      - Mergers Helmut 2013-10-25 14:38
      - IVIVC calculations mahendra 2013-10-25 16:49
        
        PCDCON ⇒ IVIVC calculations yjlee168 2013-10-27 05:41
      - IVIVC calculations thalita_m 2019-06-18 02:51
- IVIVC calculations jag009 2013-10-24 23:17
  - Minitab etc. Helmut 2013-10-25 14:43
    - Minitab etc. jag009 2013-10-25 16:27
      - XL Helmut 2013-10-25 16:38
        
        XL jag009 2013-10-28 20:42
        
        XL luvblooms 2013-10-29 05:08
        
        XL jag009 2013-10-29 15:07
        
        XL luvblooms 2013-10-30 07:00
        
        Broken link Helmut 2013-10-30 14:40
        XL jag009 2013-10-30 16:35
        
        XL luvblooms 2013-10-31 08:15
        
        XL jag009 2013-10-31 20:31
        Any news? jag009 2013-11-06 16:44
        
        Good News luvblooms 2013-11-07 10:50
        
        PBPK IVIVC jag009 2013-11-27 16:44
        
        PBPK IVIVC luvblooms 2013-11-27 19:31
        
        PBPK IVIVC jag009 2013-11-27 20:04
        
        Good News jag009 2013-11-28 06:01
        
        Contact Helmut 2013-11-07 14:50
        
        Contact jag009 2013-11-27 16:42
        
        XL thalita_m 2019-06-18 02:46
        
        Jean-Michel Helmut 2019-06-18 11:08
        
        Jean-Michel thalita_m 2019-06-20 22:18
        
        Jean-Michel Abel1972 2020-06-17 05:28
        
        Jean-Michel thalita_m 2022-09-17 05:50
    - Minitab etc. Achievwin 2020-06-17 15:00
  - IVIVC calculations mahendra 2013-10-25 16:48
- IVIVC calculations vinayshed 2013-10-28 08:54