Calculation of Intrasubject CV from CI [Power / Sample Size]

posted by d_labes  – Berlin, Germany, 2012-12-10 13:07 (4942 d 23:38 ago) – Posting: # 9704
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Dear Karthik

your calculations by hand coincide with the CV's obtained from the 90% CIs via R-package PowerTOST, function CVfromCI().

I suspect that the CV given in the EMA PAR is simply a typo.
The CI for AUC(0-inf) is very near that for Cmax. Thus the CVs should also be.

Regards,

Detlew

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