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Registersample size calculation for higher level crossover design [Power / Sample Size]
Dear all,
I have a question about sample size estimation for higher order x-over design.
When we calculate CV% of 2x2 design, MSE has to be calculated.
MSE = 2 x [(CI_high - PE) / {Root(1/nA + 1/ nB) x TINV(0.1,Df)}]^2
In case of 2x2 design, Df = nA + nB - 2
but Df of 6x3 williams design is 2n-4...
in case of 6x3 williams design, how can i get CV%? just change Df formula in MSE formula is enough?
and can i get a sample size of 2x2 crossover design using the data that i got from 6x3 williams design study?
Sincerely.
I have a question about sample size estimation for higher order x-over design.
When we calculate CV% of 2x2 design, MSE has to be calculated.
MSE = 2 x [(CI_high - PE) / {Root(1/nA + 1/ nB) x TINV(0.1,Df)}]^2
In case of 2x2 design, Df = nA + nB - 2
but Df of 6x3 williams design is 2n-4...
in case of 6x3 williams design, how can i get CV%? just change Df formula in MSE formula is enough?
and can i get a sample size of 2x2 crossover design using the data that i got from 6x3 williams design study?
Sincerely.
Complete thread:
- sample size calculation for higher level crossover designlovemysoul 2012-11-07 05:34
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- CVfromCI for higher order crossover designs d_labes 2012-11-07 08:45
Ing. Helmut Schütz