Bioequivalence and Bioavailability Forum • total (pooled) variance: examples

total (pooled) variance: examples [Power / Sample Size]

posted by Nav Coelho – 2007-07-23 21:58 (6908 d 10:22 ago) – Posting: # 927
Views: 31,673

Dear Helmut,

I really appreciate you taking the time to answer my questions in such detail. In regards to the sample size calculation for a parallel design, I agree that the worst case scenario for taking total CV as the estimate for inter CV would only result in slight overestimation in power. Thanks for the confirmation!!

As for the 60% rule, you are absolutely right. It's not a one size fits all.

Nav

Edit: Full quote removed. Please see this post! [Helmut]

Complete thread:

Sample size estimation for parallel design Nav Coelho 2007-07-20 16:14
- Parallel designs (total variance) Helmut 2007-07-20 16:29
  - Parallel designs (total variance) Nav Coelho 2007-07-20 18:38
    - CV-intra # 60% CV-inter Helmut 2007-07-22 01:17
    - total (pooled) variance: examples Helmut 2007-07-23 17:44
      - total (pooled) variance: examplesNav Coelho 2007-07-23 19:58
      - total (pooled) variance: examples BEQool 2023-04-18 09:59
        
        Higher-Order Crossovers Helmut 2023-04-20 10:19
        
        Higher-Order Crossovers BEQool 2023-04-21 07:53
        
        total (pooled) variance: examples zizou 2023-04-21 21:23
        
        total (pooled) variance: examples BEQool 2023-04-22 18:20
        
        total (pooled) variance: examples zizou 2023-04-22 21:06
        
        total (pooled) variance: examples BEQool 2023-04-25 10:57
        
        total (pooled) variance: examples zizou 2023-04-25 22:43
        
        total (pooled) variance: examples BEQool 2023-05-04 08:17
- Sample size estimation for parallel design Dipesh Jayswal 2007-07-24 08:52