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Register14 months for 1st review [Power / Sample Size]
posted by Helmut 
– Vienna, Austria, 2012-04-11 15:51 (5182 d 08:11 ago) – Posting: # 8407
Views: 9,112
Dear Detlew!
Well, guidelines are guidelines are guidelines.
Have you noticed the header on every single page?
I wouldn’t bet on it. Why not even raise the claim to 0.795?
This review amazes me in many respects. After the stuff produced by M$ Word/Excel the pages again from an IBM Selectric.
I still have no clue how they derived their CIs. If I trust in the RMSE of 0.592, the PE of 108% for nT=62, nR=60 and a simple t-test I get a CI of 90–129%. If I play around with alphas (and round the CI to integers!) it needs an α1 of 0.0008 and α2 of 0.0992 to obtain a symmetrical CI (76–124%) but then the lower CL is <80%. Should stop this stupid trial-and-error business.
❝ […] it must be stated: CI's given as ratios with 2 decimals acceptable!
❝ And that within that regulatory body which is responsible for the rule "... ![[image]](img/uploaded/IAsmall.png)
to pass a CI limit of 80 to 125, the value would be at least 80.00 and not more than 125.00 ..."
Well, guidelines are guidelines are guidelines.
Have you noticed the header on every single page?Contains Nonbinding Recommendations
Rounding off of confidence interval values:
- We recommend that confidence interval (CI) values not be rounded off; therefore, to pass a CI limit of 80 to125, the value would be at least 80.00 and not more than 125.00.
❝ I bet a case of best Czech beer that the lower limit for Cmax was something like 0.7988.
I wouldn’t bet on it. Why not even raise the claim to 0.795?
This review amazes me in many respects. After the stuff produced by M$ Word/Excel the pages again from an IBM Selectric.
I still have no clue how they derived their CIs. If I trust in the RMSE of 0.592, the PE of 108% for nT=62, nR=60 and a simple t-test I get a CI of 90–129%. If I play around with alphas (and round the CI to integers!) it needs an α1 of 0.0008 and α2 of 0.0992 to obtain a symmetrical CI (76–124%) but then the lower CL is <80%. Should stop this stupid trial-and-error business.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Parallel BE drcampos 2012-04-10 16:11
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Parallel BE Helmut 2012-04-10 17:20
- Parallel BE drcampos 2012-04-10 21:03
- FDA’s review Helmut 2012-04-11 02:22
- A reviewer which doesn't review isn't a good reviewer d_labes 2012-04-11 09:57
- 14 months for 1st reviewHelmut 2012-04-11 13:51
- Guidelines - nonbinding, Scientific advice - nonbinding … d_labes 2012-04-11 15:50
- Grumpy ol’ men Helmut 2012-04-11 16:22
- Grumpy ol’ men - OT d_labes 2012-04-11 17:04
- GDR - OT Helmut 2012-04-11 17:47
- Grumpy ol’ men - OT d_labes 2012-04-11 17:04
- Grumpy ol’ men Helmut 2012-04-11 16:22
- Guidelines - nonbinding, Scientific advice - nonbinding … d_labes 2012-04-11 15:50
- 14 months for 1st reviewHelmut 2012-04-11 13:51
- A reviewer which doesn't review isn't a good reviewer d_labes 2012-04-11 09:57
- FDA’s review Helmut 2012-04-11 02:22
- Parallel BE drcampos 2012-04-10 21:03
- Parallel BE Helmut 2012-04-10 17:20
Ing. Helmut Schütz