Sample size for ref replicate [Power / Sample Size]

posted by AB – India, 2012-03-09 13:42 (4799 d 06:44 ago) – Posting: # 8242
Views: 4,966

Dear Helmut

in one of your presentatitions it is mentioned as below

"Replicate designs
Two-sequence three-period
T R T
R T R
Sample size to obtain the same power as a 2×2×2 study: 75%
Two-sequence four-period
T R T R
R T R T
Sample size to obtain the same power as a 2×2×2 study: 50%"

could you provide the rationale to consider the sample size as 75% & 50% (of 2×2×2 study) for 3 period & 4 period replicate designs respectively?

Regards,
AB

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